USMLE : USMLE Questions & Answers

Last Updated: Sep 10, 2026

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USMLE USMLE Practice Q&A's

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USMLE USMLE Exam Syllabus Topics:

TopicDetails
Topic 1
  • Adaptive behavioral responses to stress and illness
  • Biochemistry and molecular biology
Topic 2
  • Infectious and inflammatory disorders of the eye
  • Adverse effects of drugs on the immune system
Topic 3
  • Adverse effects of drugs on the hematologic and lymphoreticular systems
  • Disorders associated with immunodeficiency
Topic 4
  • Maladaptive behavioral responses to stress and illness
  • Immunologic and inflammatory disorders
Topic 5
  • Deficiency of phagocytic cells and natural killer cells
  • Adverse effects of drugs on the nervous system
Topic 6
  • Biology of tissue response to disease
  • Disorders of balance and spatial orientation
Topic 7
  • Eating disorders and impulse control disorders
  • Pharmacodynamic and pharmacokinetic processes
Topic 8
  • Deficiency primarily of humoral immunity
  • Immunologic and inflammatory disorders

Reference: http://www.usmle.org/step-1/#question-formats

USMLE Step 1 is a one-day (8 hours) examination. It includes 322 multiple-choice questions divided into 7 blocks of 46 items (60 minutes are given for completion of each block).

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USMLE Step 2 is open to all medical students and graduates who have successfully passed the USMLE Step 1. The Step 2 exam assesses the candidates' medical knowledge, skills, and understanding of clinical science essential for patient treatment and care, health promotion and disease prevention.

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