American Society of Microbiology : ABMM Questions & Answers
Updated: May 29, 2026
No. of Questions: 204 Questions & Answers with Testing Engine
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American Society of Microbiology ABMM Sample Questions:
1. A patient presents with a chronic, non-healing skin ulcer in a tropical region. Microscopic examination of a biopsy reveals amastigotes within macrophages. Culture of the biopsy on Novy-MacNeal-Nicolle (NNN) medium yields flagellated promastigotes. The MOST likely diagnosis is cutaneous leishmaniasis caused by:
A) Trypanosoma cruzi
B) Leishmania donovani
C) Trypanosoma brucei gambiense
D) Leishmania tropica or Leishmania major
2. An immunocompromised patient returning from a trip to the southwestern United States presents with fever, cough, and chest pain. Chest X-ray shows diffuse pulmonary infiltrates. Sputum culture grows a dimorphic fungus that forms spherules containing endospores at 37°C. The MOST likely causative agent is:
A) Blastomyces dermatitidis
B) Histoplasma capsulatum
C) Paracoccidioides brasiliensis
D) Coccidioides immitis
3. A 6-year-old child presents with a pharyngitis characterized by a grayish-white pseudomembrane covering the tonsils and posterior pharynx. Gram stain of the membrane reveals Gram-positive bacilli. Culture on Loeffler's medium shows growth of metachromatic granules. The MOST significant virulence factor associated with this organism's pathogenicity is:
A) Diphtheria toxin
B) Hyaluronidase
C) Protein A
D) Streptolysin O
4. The primary mechanism of action of aminoglycoside antibiotics, such as gentamicin, involves:
A) Disruption of bacterial cell membrane integrity
B) Inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins
C) Inhibition of bacterial DNA gyrase and topoisomerase IV
D) Inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit
5. Which pattern on a Kirby-Bauer disk diffusion plate, showing resistance of Staphylococcus aureus to erythromycin but susceptibility to clindamycin with a flattening of the clindamycin zone adjacent to the erythromycin disk (D-zone test positive), indicates inducible clindamycin resistance?
A) Indicates the strain possesses the msrA gene
B) Indicates the strain possesses an erm gene and should be reported as clindamycin resistant
C) Indicates the strain should be reported as clindamycin susceptible
D) Indicates the strain is tolerant to clindamycin
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: D | Question # 3 Answer: A | Question # 4 Answer: D | Question # 5 Answer: B |
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